Privately Held
Founded 2024
USA
Candid Therapeutics is a biotechnology company focused on creating novel therapies for autoimmune diseases. The firm pioneers in the development of T-cell engager antibodies, aiming to redirect T-cells to selectively eliminate autoreactive B-cells...
https://www.candidrx.com
Privately Held
Founded 2022
USA
Solu Therapeutics is a United States–based company developing targeted therapeutics that aim to engage biological targets considered undruggable by other modalities. The company focuses on technologies and approaches intended to expand the range of...
https://solutherapeutics.com/
Publicly Traded
Founded 2021
USA
At Upstream Bio we strive to reach the source of inflammation and conquer it. Our lead program is aclinical-stage monoclonal antibody that inhibits the TSLP receptor. TSLP is a validated target positionedupstream of multiple signaling cascades that...
http://www.upstreambio.com/
Publicly Traded
Founded 2021
USA
Alumis Inc. is pioneering the development of oral therapies to transform the treatment of immune-mediated diseases. With a commitment to innovation, the company is focused on a precision approach to medication, aiming to optimize clinical outcomes...
https://www.alumis.com/
Privately Held
Founded 2023
USA
CrossBridge Bio is a Houston, United States–based biotechnology company developing next-generation dual-payload antibody–drug conjugates (ADCs). Its proprietary EGCit enzymatically cleavable linker enables site-specific attachment of two...
https://crossbridgebio.com/
Publicly Traded
Founded 2023
USA
Spyre Therapeutics develops antibody-based therapeutics for inflammatory bowel disease (IBD) and other immune-mediated diseases. The company applies antibody engineering, dosing optimization and rational therapeutic combinations to create extended...
https://spyre.com/
Privately Held
Founded 2023
USA
TwoStep Therapeutics is a biotechnology company that specializes in the development of innovative, first-in-class, multispecific targeted peptide conjugate therapies for solid tumors. The company's unique tumor-targeting polyspecific...
https://twosteptx.com/
Privately Held
Founded 2024
USA
Navigator Medicines is a clinical-stage biopharmaceutical company dedicated to advancing drug development in the field of autoimmune diseases. Utilizing their expertise in creating innovative treatments, they focus on developing bispecific...
https://www.navigatormedicines.com/
Privately Held
Founded 2021
Switzerland
Granite Bio's lead candidate is a novel monoclonal antibody for treatment of autoimmune and certain cancer indications. Granite Bio is a Swiss biotech company built through Versant Venture's discovery engine Ridgeline Discovery.
http://granitebio.com/
Privately Held
Founded 2025
USA
Biformyx BioPharma develops dual-payload antibody-drug conjugates (ADCs) for oncology. Its lead asset is a humanized monoclonal antibody targeting B7-H3 conjugated to two payloads - a cytotoxic agent and an immune-stimulating agent - intended for...
https://biformyxbio.com
Privately Held
Founded 2022
Switzerland
FimmCyte Therapeutics is a Swiss biotechnology company developing disease-modifying therapies for treatment-resistant fibrosis. Its pipeline is based on a proprietary approach called Deplete.Reprogram.Regenerate, in which assets are designed to...
https://fimmcyte.com/
Privately Held
Founded 2022
USA
Diagonal Therapeutics is at the forefront of developing agonist antibody therapeutics to tackle debilitating diseases by reactivating essential biological pathways. Their proprietary DIAGONAL platform employs advanced computational and experimental...
https://www.diagonaltx.com/
Privately Held
Founded 2021
Denmark
Commit Biologics has developed an innovative platform technology, BiCE™, that harnesses the complement system, a key component of the innate immune system, to treat cancer and autoimmune diseases. This technology uses single domain antibodies to...
https://commitbio.com/
Privately Held
Founded 2024
USA
Callio Therapeutics is a biotechnology company dedicated to advancing cancer therapy through multi-payload antibody-drug conjugates (ADCs). The company is focused on developing a HER2-targeted dual-payload ADC and another undisclosed ADC program to...
https://calliotx.com/
Privately Held
Founded 2022
USA
Revopsis Therapeutics, Inc. is dedicated to addressing blindness through the rapid discovery and development of innovative therapies using its proprietary RevMod Platform. This modular platform represents a significant advancement in multispecific...
https://revopsis.com/
Privately Held
Founded 2021
Japan
Alpha Fusion Inc. is a fusion of leading-edge scientists teaming in Nuclear Physics, Organic Chemistry, and Nuclear Medicine. We aspire to make Astatine drug discovery possible – A fusion of experts to solve various issues in supply, target...
https://alpha-fusion.com/
Privately Held
Founded 2022
Netherlands
Avidicure is at the forefront of developing innovative multifunctional antibodies known as AVC-Boosters. These advanced therapies are designed to safely and effectively deliver targeted monotherapy for cancer treatment. By activating both the innate...
https://avidicure.com/
Privately Held
Founded 2021
USA
Crossbow Therapeutics, Inc. develops immune cell engagers that recognize peptide–HLA (pHLA) complexes on cancer cells to expand the range of targets accessible to antibody-based therapeutics. Its pipeline includes T-cell engagers directed against a...
https://www.crossbowtx.com
Privately Held
Founded 2023
USA
Shinobi Therapeutics develops a class of hypoimmune CD8ab iPS-T cells for cancer, autoimmune diseases and other indications. The company engineers induced pluripotent stem cell (iPSC)-derived CD8ab T cells with immune-evasive features intended to...
https://www.shinobitx.com/
Privately Held
Founded 2021
Taiwan
PrecisemAb Biotech Co., Ltd. (Taiwan) develops disease-directed antibody therapies using its Universal Antibody Lock platform. The technology is intended to reduce systemic toxicity and to improve the safety and efficacy profile of antibody...
https://www.precisemab.com.tw/
Privately Held
Founded 2024
USA
Alys Pharmaceuticals is a leading innovator in immuno-dermatology, committed to transforming treatment paradigms across various dermatological conditions. With a focus on R&D, Alys leverages an asset-centric model to optimize therapies for...
http://www.alyspharma.com
Privately Held
Founded 2023
USA
Sail Biomedicines operates at the forefront of programmable medicines, leveraging evolution and AI to power its bioplatform and product candidates. The company utilizes first-in-category technologies, including Natural NanoParticles (NNPs) for RNA...
https://www.sail.bio/
Privately Held
Founded 2022
USA
Nona Biosciences is a leading global biotechnology company dedicated to cutting edge technology innovations. We provide a total solution for partners worldwide, from academic institutions and biotech startups to major biopharmaceutical companies....
https://www.nonabio.com/
Privately Held
Founded 2024
USA
Poplar Therapeutics, Inc. is a clinical-stage immunology company developing a new class of anti-IgE therapies. Its lead program, PHB-050, is a next-generation anti-IgE antibody with a triple-action mechanism designed to block IgE binding to mast...
https://www.poplartx.com/
Publicly Traded
Founded 2024
USA
Crescent Biopharma is dedicated to revolutionizing cancer treatment with innovative therapies focused on solid tumors. The company specializes in developing a pipeline of novel, precision-engineered biologics, positioning itself as a leader in the...
https://crescentbiopharma.com/